Table 3.
Renal Chemokine mRNA Expression in WT and IL-17A-Deficient Mice on Day 21 of GN
WT | IL-17A−/− | Normal (no GN) | |
---|---|---|---|
RANTES | 0.61 ± 0.19 | 0.72 ± 0.10 | 0.45 ± 0.35 |
MCP-1 | 0.80 ± 0.16 | 1.29 ± 0.23⁎ | 0.28 ± 0.22 |
IP-10 | 1.02 ± 0.15 | 1.17 ± 0.04 | 0.38 ± 0.25 |
TCA-3 | 0.68 ± 0.11 | 0.86 ± 0.10 | 0.19 ± 0.08 |
MIP-2 | 1.40 ± 0.26 | 1.23 ± 0.17 | 0.11 ± 0.01 |
Results are expressed relative to 18s as fold change over the mean of the WT group.
MIP-2, macrophage inflammatory protein 2; TCA-3, T-cell activation-3.
P = 0.1 versus WT.