Skip to main content
. 2011 Sep;179(3):1394–1404. doi: 10.1016/j.ajpath.2011.05.025

Figure 4.

Figure 4

B4GALNT3 suppresses cell growth and colony formation of SK-N-SH and SH-SY5Y cells. A: B4GALNT3 expression suppresses anchorage-dependent cell growth of SK-N-SH cells. MTT assays were performed to analyze the viability of SK-N-SH cells transfected with mock (open bars) or B4GALNT3 (black bars). *P < 0.01 compared with mock transfectants. B: B4GALNT3 suppresses anchorage-independent cell growth of SK-N-SH cells in soft agar. Mock (open bars) and B4GALNT3 (black bars) were seeded into soft agar for 14 days. Colony numbers (colony size >50 μm) were counted under a microscope after crystal violet staining. *P < 0.01 compared with mock transfectants. C: B4GALNT3 inhibits the viability of SH-SY5Y cells analyzed by MTT assays after plating cells for 48 hours. *P < 0.01. D: B4GALNT3 inhibits colony formation of SH-SY5Y cells in soft agar. *P < 0.01. Data are presented as mean ± SD from three independent experiments.