β-hCG expression attenuates apoptosis, up-regulates progrowth Bcl-XL, and down-regulates proapoptotic phospho-Bad in immortalized ovarian surface epithelial cells. A: Apoptosis was markedly decreased in T29 β-hCG cells relative to T29 parental cells (2.9% versus 12.3%, P < 0.05), as well as in T80 β-hCG cells relative to T80 parental cells (3.1% versus 9.2%, P < 0.05). B: Up-regulation of the prosurvival, antiapoptotic protein Bcl-XL, with a concurrent decrease in the proapoptotic phospho-Bad protein, was demonstrated in T29 β-hCG and T80 β-hCG cells, relative to parental control cells.