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. 2011 Aug 9;7(7):978–991. doi: 10.7150/ijbs.7.978

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Fig 2 — The PTPBR7 ectodomain binds specifically to highly myelinated regions in mouse brain. RAP in situ assays using BR7ecto226 (A), BR7ecto224 (B) and control PLAP protein (C) as a probe were performed on adult mouse brain cryosections. Reddish-purple staining was identified in corpus callosum (cc), alveus (alv), fimbria (fi), columns of the fornix (fx), anterior commissure of olfactory bulb (aco), hippocampal fissure (hf) in the cerebrum and cerebellar-related fiber tracts (wm). Probes BR7ecto220, BR7ecto221, BR7ecto222 and BR7ecto223 gave identical results. Bar = 1 mm.