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KdPT does not alter melanin synthesis. Normal human melanocytes were exposed to various doses of KdPT for 5 days. Bovine pituitary extracts (BPE) (containing natural melanocortins) were used as positive control. Melanin amounts in the lysed cells were determined photometrically using a synthetic melanin standard. Melanin measurements were performed in triplicate and represent mean ± SD. Data depict one of three individual experiments with identical results.
