Figure 5.

Mature DCs do not significantly express CCL18. A: Immunofluorescence staining was performed on lesional sections for the markers indicated. Occasionally, CD1c⁺ DCs expressed CCL18 in PEP and MF patch or plaque or MF tumor stage. CD208⁺ cells did not co-express CCL18. B: CD209 was only occasionally co-expressed with CD1c in MF lesional skin. CD208 was mainly co-expressed by CD1a⁺ DCs in MF patch or plaque and MF tumor lesions. C: CD11c was expressed by CD1a⁺ cells in the tumor center. Some CD163⁺ macrophages also co-expressed CD11c. CD11c⁺ cells predominately located at the tumor invasion front were co-stained with CCL18.