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. 2011 Sep;179(3):1265–1277. doi: 10.1016/j.ajpath.2011.05.042

Figure 6.

Figure 6

Inflammatory cytokines, chemotactic cytokines, and adhesion molecules are up-regulated after subretinal hemorrhage. Retinal levels of cytokines and adhesion molecules in the retina were assessed using ELISA in uninjected eyes (U) and in eyes injected subretinally 3 days before with either control (C) or autologous blood (B). Inflammatory cytokines TNF-α (A), IL-6 (B), and transforming growth factor-β (C) were generally elevated in injected eyes compared with uninjected eyes, with the highest levels in eyes injected with autologous blood. Similar trends were observed for chemotactic cytokines CCL2 (D) and SDF-1 (E) and adhesion molecules VCAM-1 (G) and ICAM-1 (H). Levels of chemokine CCL5 (F) were low and relatively unchanged. *P < 0.05).