Table 1.
Bivariate Correlates of Patient Acceptance of Hepatitis C Virus Treatment
| Treatment accepted (n=79) | Treatment refused (n=48) | |
|---|---|---|
| Patient demographics | ||
| Male gendera | 92% | 77% |
| African Americanb | 30% | 46% |
| Mean agea (years) | 48.1 | 51.2 |
| Employed | 37% | 25% |
| Any college education | 57% | 58% |
| Currently in a relationship | 26% | 17% |
| HIV and HCV disease characteristics | ||
| Mean CD4 countc (mm3) | 533 | 410 |
| CD4 count≤200c | 1% | 21% |
| Mean log10 HIV RNA (copies/mL) | 2.24 | 2.17 |
| HIV RNA≤400 | 79% | 83% |
| On ART | 91% | 96% |
| HCV genotype 1 or 4 | 72% | 81% |
| Mean log10 HCV RNA (copies/mL) | 6.09 | 6.24 |
| Psychosocial functioning | ||
| Depression (past 6 months) | 39% | 44% |
| Other psychiatric disorder (past 6 months) | 24% | 20.8% |
| Frequent alcohol use (past 6 months) | 8% | 15% |
| Illicit drug use (past 6 months)a | 11% | 27% |
| Mean ART adherence | 92% | 87% |
| Any missed ART doses (past week) | 23% | 33% |
| Any missed clinic appointments (past 6 months) | 34% | 33% |
| Provider characteristics | ||
| Number of coinfected patientsc | 309.6 | 132.0 |
| Number of patients treated with IFN/RBVb | 43.8 | 34.9 |
| Treat with small amounts of alcohol is okayc | 45% | 19% |
| Treat only if patient's drug use stopped | 44% | 57% |
| Treat only if patient's depression is in remissiona | 48% | 64% |
| Confidence to treat HCVc | 3.4 | 2.9 |
| HCV treatment outcome expectationsa | 4.3 | 4.0 |
a
p<0.05.
b
p<0.10.
c
p<0.01.
HCV, hepatitis C virus; ART, antiretroviral therapy; IFN/RBV, interferon/ribavirin.