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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Neuroimmunol. 2011 May 7;235(1-2):33–39. doi: 10.1016/j.jneuroim.2011.03.013

Figure 4.

Figure 4

Reduced B cell numbers in CD40L and CCR7 deficient mice is associated with TRA expression. (A) Immunohistochemistry staining for B220 (red) in the thymi of WT and CD40L−/− mice. (B) Frequencies of B220+CD19+ cells as obtained by FACS analysis of LNs and thymi from 4–6 week old WT and CD40L−/− mice. Solid bars-WT; open bars- CD40L−/−. (C) Real-time PCR analysis of TRA and AIRE in thymi of WT (n=3) and CD40L−/− (n=3) mice. Results are expressed relative to WT mice. Solid bars-WT; open bars- CD40L−/−. (D) Frequencies of B220+CD19+ cells as obtained by FACS analysis of LNs and thymi from 4–6 week old WT and CCR7−/− mice. Solid bars-WT; open bars- CCR7−/−. (E) Real-time PCR analysis of TRA and AIRE in thymi of WT (n=3) and CCR7−/− (n=3) mice. Results are expressed relative to WT mice. Solid bars-WT; open bars- CCR7−/−.