Table 1.
Animal Model | Cell Number per thymus × 106 |
|||
---|---|---|---|---|
DC (CD11c+) | M„U (F4/80+) | mTECs (G8.8+) | cTECs (CDR1+) | |
WT | 1.0±0.10 | 0.3±0.13 | 2.5±1.2 | 3.0±1.8 |
μMT | 0.4±0.01 | 0.3±0.07 | 1.5±0.3 | 1.0±0.4 |
LTα−/− | 0.4±0.06 | 0.2±0.05 | 1.5±0.2 | 1.2±0.3 |
LTβ−/− | 0.6±0.04 | 0.2±0.02 | 1.0±0.2 | 0.9±0.05 |
Isolated thymi from various models were analyzed for the presence of dendritic cells (DCs) macrophages (Mφ) medullary thymic epithelial cells (mTECs) and cortical thymic epithelial cells (cTECs)