Table 4. Logistic regression analysis testing the potential role of NS as a mediator between COMT rs737866 and the onset age of drug abuse*.
Predictor | Beta | t/OR | R2 | P | |
Mediation condition 1 | |||||
(dependent: NS subscale score) | rs737866 | 0.125 | 2.755 | 0.016 | 0.006 |
Mediation condition 2 | |||||
dependent: early or later onset of heroin use) | rs737866 | −0.465 | 0.628 | 0.013 | 0.013 |
Mediation condition 3 | |||||
dependent: early or later onset of heroin use) | rs737866 AND | −0.396 | 0.673 | 0.035 | 0.038 |
NS score | 0.957 | 0.001 |