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. 2011 Aug 17;6(8):e22478. doi: 10.1371/journal.pone.0022478

Table 3. Stage in research process where Three Rs-related assistance might be useful and/or acceptable, n = 306.

Stage in research process Times cited
Training on animal use 24 (8%)
Research planning (grant applications review; peer review) 28 (9%)
During preparation of animal use protocols 76 (25%)
During/after the animal use protocol review process 90 (29%)
When a problem is identified in the protocol 33 (11%)
When PIs ask for assistance 47 (15%)
On-going assistance should be provided 47 (15%)
Other 33 (11%)
Assistance should not be provided 20 (7%)