Table 2. Rates of adherence to FDA guidelines among physician-directed print advertisements in high-impact biomedical journals, overall by FDA guideline item content.a .
| Adherent, No. (%) | Non-adherent,b No. (%) | Poss. non-adherent,c No. (%) | |
| Overall | 15 (18.1) | 41 (49.4) | 27 (32.5) |
| FDA Guideline Item Content | |||
| Safety | 58 (69.9) | 9 (10.8) | 16 (19.3) |
| Efficacy | 39 (47.0) | 18 (21.7) | 26 (31.3) |
| References | 47 (56.6) | 16 (19.3) | 20 (24.1) |
| Other Issues | 53 (63.9) | 23 (27.7) | 7 (8.4) |
| Quotes (n = 2) | 1 (50.0) | 1 (50.0) | 0 (0) |
| Statisticsd (n = 24) | 22 (91.7) | 0 (0) | 2 (8.3) |
| Headlines (n = 80) | 67 (83.8) | 8 (10.0) | 5 (6.3) |
| Photographs (n = 41) | 33 (80.5) | 8 (19.5) | 0 |
Notes: NA = Non-adherence; RR = Relative Risk; CI = Confidence Interval.
a
Content domains were non-exclusively categorized.
b
Defined as non-adherent to at least 1 item in the category.
c
Defined as no non-adherent items in the category, but a response of “not sure” for at least 1 item in the category.
d
Includes statistical testing and pooling of data questions.