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. 2011 Mar 3;26(9):979–986. doi: 10.1007/s11606-011-1668-y

Table 1.

Baseline Demographic and Clinical Characteristics and P values for Comparison of Low to Adequate Literacy

Overall Sample Adequate Literacy (TOFHLA >=23) Low Literacy (TOFHLA <23) P
N(%) or Mean ± SD N(%) or Mean ± SD N(%) or Mean ± SD
Size 605 380 225
Demographics
Literacy (TOFHLA) 24.2 ± 12.3 32.7 ± 3.7 9.9 ± 7.5
Site
UNC 216 (36) 145 (38) 71 (32)
NU 166 (27) 143 (38) 23 (10)
UCSF 148 (24) 61 (16) 87 (39)
UCLA 75 (12) 31 (8) 44 (20)
Age 60.7 ± 13.1 58.7 ± 13.1 64.2 ± 12.4 P < 0.001
Race/Ethnicity P < 0.001
White NH 233 (39) 190 (50) 43 (19)
Hispanic 97 (16) 29 (8) 68 (30)
African American 232 (38) 137 (36) 95 (42)
Other 41 (7) 22 (6) 19 (8)
Missing 2 (0) 2 (1) 0 (0)
Gender: Male 314 (52) 187 (49) 127 (56) P = 0.09
Language: English 522 (87) 363 (96) 159 (72) P < 0.001
Income Level, $ P < 0.001
<15,000 305 (52) 151 (41) 154 (71)
15,000-24,999 92 (16) 61 (16) 31 (14)
25,000-40,000 67 (11) 51 (14) 16 (7)
>40,000 125 (21) 108 (29) 17 (8)
Education Level P < 0.001
<12th grade 160 (26) 46 (12) 114 (51)
High School 177 (29) 104 (27) 73 (32)
Some college 140 (23) 118 (31) 22 (10)
College graduate or greater 128 (21) 112 (29) 16 (7)
Subjective Socioeconomic Status 4.8 ± 2.5 5.4 ± 2.4 3.7 ± 2.3 P < 0.001
Insurance P < 0.001
Medicare Only 65 (11) 34 (9) 31 (14)
Medicare & Medicaid 104 (17) 49 (13) 55 (24)
Medicare & Private 129 (21) 90 (24) 39 (17)
Medicaid 151 (25) 83 (22) 68 (30)
Private 77 (13) 71 (19) 6 (3)
Uninsured 79 (13) 53 (14) 26 (12)
Overall Sample Adequate Literacy (TOFHLA > = 23) Low Literacy (TOFHLA <23) P
N(%) or Mean ± SD N(%) or Mean ± SD N(%) or Mean ± SD
Clinical Characteristics
NYHA Class P < 0.001
I 114 (19) 83 (22) 31 (14)
II 304 (50) 200 (53) 104 (46)
III 118 (20) 64 (17) 54 (24)
IV 69 (11) 33 (9) 36 (16)
Systolic Dysfunction: 355 (60) 226 (61) 129 (58) P = 0.51
Ejection fraction <0.45
Systolic BP (mm/Hg) 124.8 ± 22.7 122.0 ± 22.7 129.4 ± 22.0 P < 0.001
(N = 604) (N = 380) (N = 224)
Diastolic BP (mm/Hg) 71.3 ± 12.9 71.6 ± 12.6 70.7 ± 13.3 P = 0.38
(N = 604) (N = 380) (N = 224)
Body Mass index 33.1 ± 8.9 33.1 ± 8.9 33.1 ± 8.8 P = 0.99
(N = 602) (N = 378) (N = 224)
Creatinine level 1.26 ± 0.54 1.26 ± 0.54 1.26 ± 0.55 P = 0.93
(N = 604) (N = 379) (N = 225)
Diabetes 290 (48) 168 (44) 122 (54) P = 0.02
Hypertension 513 (85) 297 (78) 216 (96) P < 0.001
Previous MI or angina 230 (38) 122 (32) 108 (48) P < 0.001
PHQ Score 7.4 ± 5.4 7.2 ± 5.5 7.9 ± 5.3 P = 0.14
Current smoker 96 (16) 67 (18) 29 (13) P = 0.12
Medication History
ACE-I 391 (66) 245 (66) 146 (65) P = 0.96
ARB 120 (20) 72 (19) 48 (21) P = 0.49
ACE-I or ARB 497 (82) 310 (82) 187 (83) P = 0.63
Beta blocker 492 (82) 313 (83) 179 (80) P = 0.38
Spironolactone 166 (27) 119 (31) 47 (21) P = 0.01

NH = Non-Hispanic, TOFHLA = Test of Functional Health Literacy in Adults

ACE-I = Ace-inhibitor, ARB = angiotensin receptor blocker, BP = blood pressure, MI = myocardial infarction, NYHA = New York Heart Association, PHQ = Patient Health Questionnaire, TOFHLA = Test of Functional Health Literacy in Adults