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Plasma AUC at 60 minutes after injection (A), BBB PS product (B), or brain uptake (C) of [125I]-biotinyl Aβ1-40 following injection of labeled peptide either alone (open bars) or co-injected with 1:1 molar ratio of the cTfRMAb-AV fusion protein (closed bars). Data are mean ± SE (n=3 mice per point).
