Table 2.
Non-Synonymous Variants Detected in Probands With Dilated Cardiomyopathy
| Amino acid | Nucleotide | Controls | DCM | HCM | |||
|---|---|---|---|---|---|---|---|
| N=509 | N=383 | N=307 | |||||
| A | C | A | C | A | C | ||
| 316 | 193 | 179 | 204 | 49 | 258 | ||
| p.N128K | g.474C>G | 0 | 0 | 1 | 0 | 0 | 0 |
| p.R140W | g.7721C>T | 0 | 0 | 0 | 1 | 0 | 0 |
| p.L153P | g.7761T>C | 0 | 0 | 1 | 0 | 0 | 0 |
| p.S307T | g.8223G>C | 0 | 0 | 0 | 1 | 0 | 0 |
| p.P324L | g.8274C>T | 0 | 0 | 3 | 0 | 0 | 0 |
| p.S364L | g.8394C>T | 0 | 0 | 1 | 0 | 0 | 0 |
| Total number of non-synonymous variants per group and ethnic background | 0 | 0 | 6 | 2 | 0 | 0 | |
| Total number of non-synonymous variants per group | 0 (0 %) | 8 (2.1%) | 0 (0%) | ||||
Abbreviations: As in Table 1., A: African Americans; C: Caucasians