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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Mol Cancer Res. 2011 Jun 10;9(8):997–1007. doi: 10.1158/1541-7786.MCR-10-0490

Figure 3. E-cadherin and N-cadherin co-expression among CD45 negative nucleated cells from men with metastatic CRPC.

Figure 3

All panels represent merged images derived from phase/DAPI, CD45/DAPI, E-cadherin(E-cad)/DAPI, and N-cadherin(N-cad)/DAPI expression as indicated. (A) a leukocyte with CD45 expression, (B) a CD45 negative nucleated cell, with E-cadherin and N-cadherin co-expression, (C) a CD45 negative nucleated cell with N-cadherin expression and no E-cadherin expression, (D) a CD45 negative nucleated cell with E-cadherin expression and no N-cadherin expression, and (E) a nucleated cell lacking expression of CD45, E-cadherin, and N-cadherin. Scale bars represent 20 μm and were added from an image taken at identical magnification and resolution. Control cells were assayed in parallel at the same time of CTC collection and analysis with each set of patient samples and are shown in Supplementary Figure 1.