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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Respir Physiol Neurobiol. 2011 Mar 5;179(1):34–42. doi: 10.1016/j.resp.2011.03.002

Fig. 4.

Fig. 4

The reversal potential of glycine-receptor-mediated currents recorded in HMs becomes more hyperpolarized with postnatal development. (A) Local glycine application onto a voltage-clamped HM shows the reversal potential from a neonate (P2) and a juvenile (P15) rat. Various holding potentials indicated in mV. (B) Neonate and juvenile group data for the current-voltage relationship of the glycine-evoked responses. Results show the hyperpolarizing shift in the glycine-evoked response with postnatal development. All recordings were done using the gramicidin perforated-patch technique so as not to disturb the native intracellular chloride concentration. (Adapted from Singer et al., 1998).