Table 2.
dHPLC |
HRM |
|||||||
---|---|---|---|---|---|---|---|---|
Method | Positive (no.) | Negative (no.) | Sensitivity [% (95% CI)] | Specificity [% (95% CI)] | Positive (no.) | Negative (no.) | Sensitivity [% (95% CI)] | Specificity [% (95% CI)] |
TaqMan | ||||||||
Positive | 13 | 2 | 90 (77.4–100) | 100 (99.7–100) | 16 | 3 | 84.2 (65.2–100) | 97.4 (94.5–100) |
Negative | 0 | 151 | 4 | 147 | ||||
Direct sequencing | ||||||||
Positive | 12 | 1 | 93.8 (78.8–100) | 98.6 (96.4–100) | 14 | 2 | 87.5 (68.2–100) | 95.7 (91.9–99.4) |
Negative | 1 | 136 | 6 | 132 |