Table 2.
Summary of Diagnosis, DNA and Array Parameters, SNP array, and STR Results for Chromosomes 1p and 19q
| Case no. | Diagnosis | DNA quality | DNA input (ng) | Log R Dev | SNP array results |
STR results |
||
|---|---|---|---|---|---|---|---|---|
| 1p | 19q | 1p | 19q | |||||
| 1 | ODG | Excellent | 200 | 0.21 | del 1p | del 19q | LOH | LOH |
| 2 | ODG | Excellent | 200 | 0.45 | del 1p | del 19q | LOH | LOH |
| 3 | ODG | Good | 180 | 0.52 | del 1p | del 19q | LOH | LOH |
| 4 | ODG | Good | 184 | 0.55 | del 1p | del 19q | LOH | LOH |
| 5 | ODG | Good | 76 | 0.39 | del 1p | del 19q | LOH | LOH |
| 6 | ODG | Good | 200 | 0.57 | del 1p | del 19q | LOH | LOH |
| 7 | ODG | Good | 200 | 0.52 | del 1p | del 19q | LOH | LOH |
| 8 | ODG | Good | 200 | 0.50 | del 1p | del 19q | LOH | LOH |
| 9 | ODG | Excellent | 120 | 0.34 | del 1p | del 19q | LOH | LOH |
| 10 | Anaplastic ODG | Intermediate | 180 | 0.98 | del 1p | del 19q | LOH | LOH |
| 11 | Anaplastic ODG | Excellent | 156 | 0.34 | del 1p | del 19q | LOH | LOH |
| 12 | Anaplastic ODG | Good | 176 | 0.35 | del 1p | del 19q | LOH | LOH |
| 13 | Anaplastic ODG | Good | 200 | 0.39 | del 1p | del 19q | LOH | LOH |
| 14 | Anaplastic ODG | Good | 200 | 0.41 | del p12→pter | del q13.11→qter | LOH | LOH |
| 15 | ODG + oligosarcoma | Excellent | 116 | 0.35 | del/CN-LOH 1p | del/CN-LOH 19q | LOH | LOH |
| 16 | Fibrillary AC | Excellent | 172 | 0.44 | No abnl | No abnl | No LOH | No LOH |
| 17 | Fibrillary AC | Good | 200 | 0.60 | No abnl | No abnl | No LOH | No LOH |
| 18 | Fibrillary AC | Intermediate | 200 | 1.07 | No abnl | No abnl | No LOH | No LOH |
| 19 | AC | Excellent | 200 | 0.51 | No abnl | No abnl | No LOH | No LOH |
| 20 | AC | Intermediate | 200 | 0.83 | No abnl | No abnl | No LOH | No LOH |
| 21 | Pineal parenchymal tumor | Excellent | 148 | 0.27 | No abnl | No abnl | No LOH | No LOH |
| 22 | Anaplastic AC | Excellent | 200 | 0.22 | No abnl | No abnl | No LOH | No LOH |
| 23 | Anaplastic AC | Excellent | 200 | 0.25 | No abnl | del q13.41→qter | No LOH | No LOH |
| 24 | Anaplastic AC | Excellent | 200 | 0.33 | del p31.1p31.1 | No abnl | No LOH | No LOH |
| 25 | Anaplastic AC | Good | 200 | 0.38 | No abnl | del q13.32→qter | No LOH | No LOH |
| 26 | Anaplastic AC | Excellent | 160 | 0.37 | No abnl | del q13.31→qter | No LOH | LOH |
| 27 | Anaplastic AC | Good | 190 | 0.43 | No abnl | del cen→q13.42 | No LOH | LOH |
| 28 | Glioblastoma | Excellent | 152 | 0.46 | No abnl | del q13.31→q13.32; | No LOH | LOH |
| del q13.32→qter | ||||||||
| 29 | Glioblastoma | Excellent | 200 | 0.25 | del p35.1→ p36.11 | dup entire chromosome | No LOH | LOH |
| 30 | Anaplastic AC | Good | 192 | 0.24 | del p32.1→pter, dup p13.3p13.3 | del p12→qter | Distal LOH | LOH |
AC, astrocytoma; del, deletion; dup, duplication; No abnl, no abnormality detected; ODG, oligodendroglioma.