Table II.
In vitro follicle growth characteristics of follicles isolated from mice of different ages, weights or in different stages of the estrous cycle.
| A | D49 | D100 | D270 | D100* |
|---|---|---|---|---|
| # of mice | 21 | 19 | 20 | 15 |
| # Follicles isolated | 298 | 260 | 120 | 180 |
| # Follicles/mouse | 14.2 ± 1.1* | 13.8 ± 0.8* | 6.2 ± 0.6 | 11.8 ± 1.3 |
| Terminal follicle diameter (µm) | 306.1 ± 6.2 | 306.0 ± 0.8** | 301.6 ± 12.5 | 323.3 ± 5.4 |
| Survival in culture (%) | 84.2 ± 1.7*** | 83.0 ± 2.4*** | 72.1 ± 5.0 | 77.5 ± 3.5 |
| B | Estrus | Metestrus | Diestrus | |
| # of mice | 6 | 8 | 7 | |
| # Follicles isolated | 92 | 104 | 102 | |
| # Follicles/mouse | 15.3 ± 1.1 | 13.0 ± 2.3 | 14.6 ± 1.5 | |
| Terminal follicle diameter (µm) | 314.9 ± 9.5 | 308 ± 13.14 | 298.1 ± 5.9 | |
| Survival in culture (%) | 83.5 ± 2.6 | 88.5 ± 3.3**** | 78.2 ± 1.4 | |
*P<0.05 versus D270.
**P=0.05 versus D100*.
***P<0.001 versus D270.
****P<0.05 versus diestrus.