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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 May 10;20(7):1447–1452. doi: 10.1158/1055-9965.EPI-11-0190

Table 1.

Association between copy number variants of the GSTM1 and GSTT1 and endometrial cancer risk in the pooled NHS and WHS data

Cases Controls ORa 95% CI
GSTM1
  0 232 621 1.00 -
  1 156 442 0.96 0.74–1.24
  2/3 39 114 0.82 0.52–1.27
  Ptrend 0.41
  carrier 195 556 0.93 0.73–1.19
GSTT1
  0 64 239 1.00 -
  1 199 526 1.33 0.92–1.92
  2/3 157 401 1.51 1.04–2.19
  Ptrend 0.04
  carrier 356 927 1.41 1.00–1.99
GSTM1/GSTT1 combinations
  null/null 36 125 1.00 -
  null/carrier 193 482 1.33 0.85–2.08
  carrier/null 28 108 0.83 0.46–1.52
  carrier/carrier 161 431 1.23 0.78–1.94
a

Conditional logistic regression adjusted for matching factors and smoking at diagnosis, age at menarche, age at first birth and parity, BMI (kg/m2) at diagnosis, postmenopausal hormone use at diagnosis, menopausal status and age at menopause at diagnosis, ever oral contraceptive use