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. Author manuscript; available in PMC: 2011 Aug 18.
Published in final edited form as: Clin Infect Dis. 2010 May 15;50(10):1387–1396. doi: 10.1086/652283

Table 6.

Adjusted Cause-Specific Incidence Rate Ratios by Time Receiving Antiretroviral Therapy (ART) and Calendar Year of Starting ART, from Poisson Models

Model Cause of death
AIDS Non-AIDS malignancy Non-AIDS infection Cardiovascular disease Violence Liver related Respiratory Renal failure
Time receiving ARTa
    <1 year 1 1 1 1 1 1 1 1
    1–1.99 years 0.50 (0.41–0.61) 0.85 (0.52–1.38) 0.68 (0.42–1.10) 0.92 (0.51–1.65) 1.24 (0.71–2.18) 0.72 (0.39–1.33) 1.53 (0.51–4.60) 0.48 (0.15–1.53)
    ≥2 years 0.33 (0.28–0.39) 1.24 (0.84–1.82) 0.63 (0.42–0.96) 1.22 (0.76–1.96) 1.17 (0.72–1.89) 0.90 (0.57–1.43) 1.07 (0.37–3.13) 0.38 (0.15–0.95)
    P, for trend <.001 .18 .036 .32 .61 .80 .96 .042
Year of starting ARTb
    1996–1997 1 1 1 1 1 1 1 1
    1998–1999 0.82 (0.69–0.99) 0.77 (0.54–1.09) 0.66 (0.40–1.09) 0.85 (0.55–1.32) 1.26 (0.83–1.93) 1.01 (0.65–1.58) 1.88 (0.59–6.00) 0.62 (0.22–1.71)
    2000–2002 0.70 (0.58–0.85) 0.66 (0.45–0.98) 1.09 (0.68–1.73) 0.78 (0.49–1.26) 0.66 (0.38–1.14) 0.72 (0.43–1.21) 1.17 (0.32–4.25) 0.52 (0.17–1.52)
    2003–2006 0.72 (0.56–0.92) 0.83 (0.47–1.46) 1.63 (0.92–2.92) 0.74 (0.35–1.56) 1.02 (0.48–2.18) 0.42 (0.16–1.13) 3.09 (0.74–12.95) 0.56 (0.14–2.30)
    P, for trend <.001 .11 .074 .28 .33 .059 .32 .28

NOTE. Data are hazard ratio (95% confidence interval), unless otherwise indicated.

a

Adjusted for age, sex, injection drug use, CD4, log viral load, AIDS at baseline, and year of starting ART.

b

Adjusted for age, sex, injection drug use, CD4, log viral load, AIDS at baseline, and time receiving ART.