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. 2011 Sep-Oct;102(Suppl 1):S19–S27. doi: 10.1093/jhered/esr022

Table 2.

ACE gene marker 56 shows P value scores ≤0.001 in separate association tests of Alaskan sled dogs and Purebred breeds

Group Marker Chromosome Location (bp) Gene position Allele Case MAF Control MAF P value
Sled doga 56 9 14635693 Intron 19 A:G 0.031 0.305 2.38 × 10−05
Purebreedb 56 9 14635693 Intron 19 A:G 0.265 0 7.57 × 10−08
a

SNP association test comparing 34 elite distance dogs (cases) and 49 elite sprint dogs (controls).

b

SNP association test comparing 10 Alaskan Malamutes and 10 Siberian Huskies (20 cases) and 60 purebred dogs (10 dogs from each of the following breeds; Whippet, Greyhound, Mastiff, Staffordshire Bull Terrier, English Pointer, and German Shorthaired Pointer).