Table 2.
Toxicity Grade by Treatment Phase | Toxicity |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heme |
GI |
Fatigue |
Neuropathy |
Infusion Reaction |
HFS |
Acneiform Rash |
Other |
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No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
Induction chemotherapy phase (n = 69) | ||||||||||||||||
Grade 2 | — | 19 | 28 | 14 | 30 | 6 | 9 | 2 | 3 | — | 36 | 52 | 6 | 9 | ||
Grade 3 | 7 | 10 | 7 | 10 | 2 | 3 | 1 | 1 | 2 | 3 | — | 2 | 3 | — | ||
Grade 4 | 2 | 3 | — | — | — | — | — | — | — | |||||||
Total grades 3 and 4 | 9 | 13 | 7 | 10 | 2 | 3 | 1 | 1 | 2 | 3 | — | 2 | 3 | — | ||
Chemoradiation phase (n = 60) | ||||||||||||||||
Grade 2 | 1 | 2 | 14 | 23 | 8 | 13 | — | — | 3 | 5 | 22 | 37 | — | |||
Total grades 3 and 4 | 1 | 2 | 2 | 3 | — | — | — | — | 1 | 2 | ||||||
Induction or chemoradiation phase (n = 69) | ||||||||||||||||
Grade 2 | — | 22 | 32 | 18 | 26 | 6 | 9 | 2 | 3 | 3 | 5 | 37 | 54 | 6 | 9 | |
Grade 3 | 7 | 10 | 7 | 10 | 4 | 6 | 1 | 1 | 2 | 3 | — | 2 | 3 | — | ||
Grade 4 | 2 | 3 | — | — | — | — | — | — | — | |||||||
Total grades 3 and 4 | 9 | 13 | 7 | 10 | 4 | 6 | 1 | 1 | 2 | 3 | — | 2 | 3 | — |
Abbreviations: Heme, hematologic toxicity; HFS, hand-foot syndrome.