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. 2001 Apr 26;5(3):158–166. doi: 10.1186/cc1016

Table 1.

Effects (means ± SD) of prolonged hypoxia in five anesthetized control piglets

	Normoxia	1 h hypoxia	2 h hypoxia	3 h hypoxia	4 h hypoxia
Cardiac index (ml kg^-1 min^-1)	136 ± 25	151 ± 49^*	154 ± 50^*	151 ± 35^*	142 ± 43
Arterial saturation (%)	99 ± 0.5	61 ± 6^*	63 ± 3^*	59 ± 4^*	60 ± 4^*
Systemic DO₂ (ml kg^-1 min^-1)	20 ± 3.4	14 ± 2.2^*	13 ± 1.6^*	14 ± 3.7^*	13 ± 3.7^*
SAP (mmHg)	83 ± 20	79 ± 15	79 ± 15	75 ± 15	73 ± 16^*
PAP (mmHg)	25 ± 2	37 ± 7^*	37 ± 7^*	38 ± 7^*	40 ± 6^*
PVRI (mmHg ml^-1 kg^-1 min^-1)	0.19 ± 0.04	0.27 ± 0.11^*	0.25 ± 0.09^*	0.26 ± 0.07^*	0.30 ± 0.06^*
SAP/PAP ratio	3.3 ± 0.6	2.2 ± 0.5^*	2.2 ± 0.5^*	2.0 ± 0.4^*	1.8 ± 0.4^*
Systemic EO₂ (%)	27 ± 5.5	46 ± 14^*	44 ± 13^*	43 ± 13^*	44 ± 11^*

EO₂, oxygen extraction; DO₂, oxygen delivery. ^*P < 0.05 compared with normoxic baseline.