Table 2. Counts of non-reference MEI contained by annotated function regions.
Gene | UTR | CDS | Total | |
ALU | 1438 | 32 | 2 | 4499 |
L1 | 249 | 4 | 0 | 792 |
SVA | 31 | 0 | 1 | 79 |
Total | 1718 | 36 | 3 | 5370 |
Expected total | 2020 | 105 | 137 | - |
Suppression factor | 1.2 | 2.9 | 45.7 |
Detected events subsequently invalidated by PCR are not counted. Expected counts of insertions were calculated according to random placement across the genome. The p-value that the observed number of CDS interrupting MEI is consistent with random placement is <10−50.