Table 2. Distribution of type three secretion systems encoded by SPI-1 (T3SS-1) and SPI-2 (T3SS-2) and their secreted effectors in the salmonellae.
Salmonella species/serotypes | |||||||||
S.bongori 12419 | S. Typhi CT18 | S.Typhimurim LT2 | S. Enteritidis P125109 | S. Gallinarum 287/91 | S.Cholerasuis SC-B67 | S. arizonae CDC346-86 | |||
Secretion system | T3SS effector systems | ||||||||
Presence/absence | |||||||||
T3SS-1 | + | + | + | + | + | + | + | ||
T3SS-2 | − | + | + | + | + | + | + | ||
T3SS effector proteins | |||||||||
Genomic Location | Secreted by | Gene name | Presence/absence | ||||||
øGifsy-1 | SPI-2 | gogB | − | − | + | − | − | + | − |
SPI-5 | SPI-2 | pipB | − | + | + | + | + | + | − |
ROD | SPI-2 | pipB2 | − | + | + | + | + Ψ | + | − |
BB | SPI-2 | sifA | − | + | + | + | + | + | + |
BB | SPI-2 | steA | − | + | + | + | + | + | − |
BB | SPI-2 | sifB | − | + | + | + | + Ψ | + | + |
BB | SPI-2 | steB | − | − | + | + | + | + | − |
BB | SPI-2 | steC | − | + | + | + | + | + | − |
BB | SPI-1 & 2 | slrP | + | + Ψ | + | + Ψ | + Ψ | + Ψ | + |
BB | SPI-1 | sopA | −* | + Ψ | + | + | + Ψ | + Ψ | − |
SPI-2 | SPI-2 | spiC (ssaB) | − | + | + | + | + | + | + |
SPI-5 | SPI-1 | sopB (sigD) | + | + | + | + | + | + | + |
BB | SPI-1 | sopD | + | + | + | + | + | + | + |
BB | SPI-2 | sopD2 | − | + Ψ | + | + | + | + | + |
øSopE and øSE12 | SPI-1 | sopE | − | + | − | + | + | − | − |
BB | SPI-1 | sopE2 | + | + Ψ | + | + | + | + | + |
SPI-1 | SPI-1 | avrA | + | − | + | + | + | − | − |
SPI-1 | SPI-1 | sptP | + Ψ | + | + | + | + | + | + Ψ |
SPI-1 | SPI-1 | sipA (sspA) | + | + | + | + | + | + | + |
SPI-1 | SPI-1 | sipB (sspB) | + | + | + | + | + | + | + |
SPI-1 | SPI-1 | sipC (sspC) | + | + | + | + | + | + | + |
SPI-2 | SPI-2 | sseF | − | + | + | + | + | + | + |
SPI-2 | SPI-2 | sseG | − | + | + | + | + | + | + |
BB | SPI-2 | sseL | − | + | + | + | + | + | + |
øGifsy2 | SPI-2 | sseI (srfH) | − | − | + | + | − | + Ψ | + |
BB | SPI-2 | sseJ | − | + Ψ | + | + | + | + | + |
ROD | SPI-2 | sseK1 | − | − | + | + | + Ψ | + | + |
ROD | SPI-2 | sseK2 | − | − | + | − | − | − | − |
øSE20 | - | sseK3 | − | − | −& | + | − | − | − |
ROD | SPI-1 & 2 | sspHI | − | − | +@ | − | − | − | − |
SPI-12 | SPI-2 | sspH2 | − | + | + | + | + Ψ | + Ψ | + |
pSLT plasmid | SPI-2 | spvB | − | − | + | + | + | − | + |
+, present; -, absent; Ψ, pseudogene;
*, see sboH: a chimera of sopA and a Non-LEE-encoded Type III secretion system effector gene nleH1; BB, chromosomal backbone; ROD, region of difference/genomic island;