Figure 4. CD40 deficiency inhibits NF-κB activation in the carotid artery wall after ligation injury.

Representative cross-sections from carotid artery immunostained for total NF-κB p65 (A) and activated phospho-p65 (Ser536) (B), as well as their quantitative analysis, in WT and CD40^−/− mice (n = 5 per group). Arrows indicate the internal elastic lamina. Scale bars: 20 µm. Data are expressed as mean ± SEM. ** P<0.01 versus corresponding WT.