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. 2011 Aug 18;6(8):e23489. doi: 10.1371/journal.pone.0023489

Table 3. Descriptive statistics of serum GFAP measurements (pg/mL) in patients without optic nerve disease1 are shown.

NMO (pg/mL) ‘RION’ (pg/mL) ‘CRION’ (pg/mL) R+C (pg/mL)
Mean 6.46 2.71 3.16 2.94
Std Dev1 4.68 2.28 2.29 2.22
C.I. of Mean2 4.91 1.91 1.91 1.18
Median 5.76 2.58 2.56 2.58
25% 3.30 0.80 1.46 0.95
75% 7.21 4.16 4.39 4.39
Skewness 1.45 0.62 1.08 0.75
Kurtosis 2.72 −0.45 1.12 −0.09
99% C.I.3 7.70 2.82 2.83

AQP4+ON patients showed the highest levels of serum GFAP as well as the highest variance. Both the median and mean values for serum GFAP level are higher in AQP4+ON patients compared to the values in the NMO spectrum group as a whole (4.63 pg/mL, 5.90 pg/mL). All values are stated to within 2 decimal places.

1

Std Dev = standard deviation.

2

C.I. = Confidence Interval.

3

ON = optic neuritis, AQP4+ON = Aquaporin 4 autoantibody positive ON, ‘CRION’ = ‘chronic relapsing inflammatory optic neuropathy’, ‘RION’ = Recurrent Isolated Optic Neuritis.