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. 2011 Aug 18;6(8):e23694. doi: 10.1371/journal.pone.0023694

Figure 3. Comparison of indenotryptoline and indolocarbazole biosynthetic gene clusters.

Figure 3

(A) Indenotryptoline gene clusters. Top to bottom: Cladoniamide and BE-54017 [13] gene clusters. (B) Indolocarbazole gene clusters. Top to bottom: rebeccamycin [10], AT2433 [16], K252a [17], staurosporine (from Streptomyces sp. TP-A0274 and putative cluster from Streptomyces clavuligerus) [9], [19], and staurosporine (putative cluster from Salinispora arenicola) [15] gene clusters. Note that inkE is the homolog to rebC in the K252a gene cluster, and the Salinispora arenicola staurosporine gene cluster lacks a staMB homolog.