Table 2.
Days a | Groups | ||||
---|---|---|---|---|---|
IgG1 | IgG2a | IgG1/IgG2a ratio | |||
pVAX1/hsp60 | pVAX1 | pVAX1/hsp60 | pVAX1 | ||
15 | 0.06 ± 0.039b | 0.002 ± 0.001 | 0.03 ± 0.011b | 0.003 ± 0.002 | 2.00 |
30 | 0.23 ± 0.094b | 0.003 ± 0.001 | 0.27 ± 0.149b | 0.002 ± 0.001 | 0.85 |
45 | 0.24 ± 0.133b | 0.004 ± 0.002 | 0.43 ± 0.114b | 0.004 ± 0.001 | 0.56 |
60 | 0.32 ± 0.165b | 0.003 ± 0.002 | 0.49 ± 0.160b | 0.004 ± 0.003 | 0.65 |
a Days after the first immunization.
b Significantly different compared to mice immunized with the pVAX1 vector.