Table 3.
Sensitivity Analyses
| Lobar ICH | Deep ICH | |
|---|---|---|
| RR of ICH while receiving statins | Threshold (basecase 1.68; range: 1–2.6) | |
|
| ||
| Primary prevention | 1.03 | 1.20 |
| Prior MI | 1.07 | 1.50 |
| Prior ischemic stroke | 1.06 | 1.41 |
|
| ||
| ICH Annual Recurrence probability | Threshold (range: 0–15%)† | |
|
| ||
| Primary prevention | 0.6 | 0.6 |
| Prior MI | 1.6 | 1.5 |
| Prior ischemic stroke | 1.3 | 1.3 |
|
| ||
| 10-Year CVD Probability | Threshold (range: 0–80%) | |
|
| ||
| PP | * | 0.46 |
|
| ||
| MI Annual Recurrence probability | Threshold (range: 0–80%) | |
|
| ||
| Prior MI | 20 (5.9 × base case) | 4.6 (1.4 × base case) |
†
Basecase annual recurrence rate for lobar ICH – 14%/year; deep ICH – 1.7%/year.
*
Statin never preferred. For RR of ICH thresholds, 10-year CVD probability was set to 20%. For 10-year CVD probability thresholds, RR of ICH was set to 1.68.