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. 2011 Aug 1;108(33):13829–13834. doi: 10.1073/pnas.1105121108

Fig. 7.

Fig. 7.

CSE deficiency exacerbates the development of endothelial dysfunction in thoracic aortic rings placed in elevated extracellular glucose. ACh-induced relaxations in aortic rings from wild-type (CSE+/+; A) or CSE−/−(B) mice placed in low (LG) or high (HG) glucose for 24 h. *P < 0.05 shows significant inhibition of relaxations in CSE−/− rings. C shows a comparison of the percentage decrease of the relaxation by high glucose between CSE+/+ and CSE−/− mice; *P < 0.05 shows a higher degree of impairment of the relaxations in the CSE−/− rings than in wild-type rings (n = 6–12).