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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Jun 16;31(9):2063–2069. doi: 10.1161/ATVBAHA.111.225870

Figure 2.

Figure 2

IGBS reduced macrophage infiltration and MCP-1 expression in MAT of diabetic mice. A, Immunohistochemical staining shows that Mac-3 positive macrophage infiltration in MAT was higher in Leprdb+Sham versus IGBS. Data shown are representative of 4 separate experiments. B, mRNA expression of CD68 was increased in MAT of Leprdb+Sham. IGBS significantly reduced CD68 mRNA levels in MAT. The mRNA (C) and protein (D) expression of MCP-1 were increased in MAT of Leprdb+Sham, and were reduced by IGBS. Data represent mean±SEM, n=4-12 mice. *P<0.05 compared with m Leprdb+Sham surgery; # P<0.05 compared with Leprdb+Sham surgery.