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Mfp-3 variants are secreted into the distal depression (a) and partially adsorbed by dopa mediated H-bonds to the mica surface. The oxidation of unadsorbed dopa to dopa-quinone (b) is counteracted by reducing thiolates (c) in mfp-6, which enables enhanced adsorption (d). Depletion of thiolate pairs in mfp-6 transforms mfp-6 into a cross-linker with mfp-3 (e).
