Table 4.
Effects of anti-TNF during in vitro maturation on oocyte meiotic maturation and subsequent embryonic development following IVF/IVC.
| Anti-TNF concentration |
Meiotic maturation (n) |
Cleaved embryos (n) |
Blastocyst development (n) | Blastocyst/cleaved § | Blastocyst cell number (n) |
|---|---|---|---|---|---|
| 0 µg/ml | 56.6 ± 6.9%a (53) | 53.8 ± 2.7%a (291) | 17.7 ± 2.0%a (291) | 33.4 ± 3.7%a | 42.9 ± 2.4 (51) |
| 100 µg/ml | 31.4 ± 8.0%b (35) | 39.2 ± 4.2%b (119) | 9.9 ± 2.6%b (119) | 24.2 ± 6.9%b | 51.1 ± 8.9 (12) |
ab
Different superscripts within a column denote a significant difference, P < 0.05. Data are reported as mean ± SEM.
§
Percentage of blastocysts is calculated from the cleaved embryos.