Figure 2.
mRNA levels for IL-1β, IL-6 and TNFα in biopsies of the nucleus tractus solitarii in control (N) rats and after 7 days of chronic hypoxia (H). Cytokine expression is normalized to B2M in the top panel and RPL13A in the lower panel. TNFα was not affected significantly by any treatment. Chronic hypoxia significantly increased IL-1β and IL-6 (HS vs. NS) and this was blocked by ibuprofen (HI vs. HS). * p<0.05, 1-tailed, n = 5 except n= 4 for IL-1β in HS.