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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biopharm Drug Dispos. 2011 Jul 28;32(6):355–367. doi: 10.1002/bdd.764

Fig. 1.

Fig. 1

Effect of different xenobiotic drugs on miRNA expression in human breast cancer (MCF-7) cells. Cells were treated with different xenobiotic drugs (Table 1). Total RNA was isolated with Trizol reagent and reverse transcribed using specific primers (Supplemental Table S1). Individual miRNAs were profiled by qPCR analyses. miRNA level was normalized to small RNA U74 and compared to that (set as 1-fold) of vehicle control. Values represent mean ± SD of triplicate cultures repeated twice (N = 6). *P < 0.05 as compared to vehicle control.