Table 1.
Characteristics | Caucasians (n=336) |
African Americans (n=224) |
P |
---|---|---|---|
Men/Women | 217/119 | 126/98 | 0.052 |
Age, yrs | 56.8±0.6 | 54.8±0.6 | 0.025 |
BMI, kg/m2 | 29.7±0.3 | 28.6±0.4 | 0.043 |
Systolic blood pressure, mm Hg | 125±1 | 129±2 | 0.058 |
Diastolic blood pressure, mm Hg | 75±1 | 78±1 | 0.004 |
Postmenopausal (%) | 92 (79%) | 65 (66%) | 0.032 |
Inflammatory markers | |||
CRP, mg/L | 7.0±0.6 | 9.8±1.0 | 0.004 |
SAA, mg/L | 82±8 | 111±13 | 0.284 |
Fibrinogen, mg/dL | 328±5 | 383±7 | <0.001 |
Lp-PLA2 mass, ng/mL | 293±4 | 232±5 | <0.001 |
Lp-PLA2 activity, nmol/min/mL | 173±2 | 141±3 | <0.001 |
PTX-3, ng/mL | 2.33±0.15 | 1.87±0.23 | <0.001 |
Data are expressed as mean ± SEM. Data for CRP, SAA, Lp-PLA2 mass, Lp-PLA2 activity and PTX-3 were logarithmically transformed to normalize the distribution of marker values before statistical analyses.