Figure 3.

Pharmacological contributions to NIC-induced EEG desynchronization and EMG activation. Each graph represents the difference in parameters (a, EEG total power; b, VTA total power; c, EMG total power; d, cortical α power; e, cortical β power; f, cortical γ power) between NIC 30 μg/kg and saline. Values with significant between-group differences (p<0.05; Student's t-test) are shown as black filled symbols. Time intervals corresponding to the first significant differences (ie, prevalence of pharmacological over non-pharmacological factors) are specified in right bottom corner of each graph. Vertical hatched lines at 0 and 15 s indicate the duration of injection, horizontal hatched lines at 0% represent a zero difference between groups.