Table 3.
Outcome of First Episode Depression, Totally and by Age-Of-Onset
| Characteristic | Total (N=301) | Age ≤ 30 Years (N=99) | Age > 30 Years (N=202) | P 1 | B /OR (95% CI)2 Early vs late Onset (Adjusted for Gender) | P 3 |
|---|---|---|---|---|---|---|
| Remission on first-line treatment, N (%) | 79 (29.2) | 27 (31.8) | 52 (28.1) | 0.5 | 1.3 (0.7-2.4) | 0.4 |
| Mean Ham-D 17 score at endpoint (S.D.) 4 | 9.3 (6.2) | 8.9 (5.8) | 9.4 (6.3) | 0.5 | 0.6 (-0.9-2.2) | 0.4 |
| Mean BDI 21 score at endpoint (S.D.) 5 | 15.3 (9.9) | 18.4 (10.3) | 13.8 (9.4) | <0.0005 | -3.4 (-5.8- -0.9) | 0.008 |
1
P-values (2-sided) in univariate analyses comparing patients with early and late onset (χ2-test categorical data and t-test for continuous data)
2
Correlation coefficients in multiple regression models / odds-ratios in logistic regression model; the effect of age-of-onset adjusted for the affect of gender
3
P-values (2-sided) in the regression models
4
17-item Hamilton Depression Rating Scale (Ham-D 17)
5
21-item Beck Depression Inventory (BDI 21)