Table 2.
Gene repertoires for amino acid and vitamin/cofactor biosynthesis in C. difficile (CD), C. novyi (CN) and SFB
| Organisms | CD | CN | SFB |
|---|---|---|---|
| Amino acids | |||
| Glycine, serine and threonine | serA | serA | serA |
| serB | serB | ||
| glyA | glyA | glyA | |
| thrBC | thrBC | ||
| hom | hom | ||
| Cysteine and methionine | cysEK | cysEK | |
| metAY | metAY | ||
| metC | metC | ||
| metH | metH | ||
| metK | metK | metK | |
| Valine, leucine and isoleucine | ilvA | ilvA | |
| ilvBCD | ilvBCD | ||
| ilvE | ilvE | ||
| leuABCD | |||
| Lysine | dapABCDEFG | dapABCDEFG | dapABDFG |
| lysA | lysA | lysA | |
| glnA | glnA | glnA | |
| Alanine, aspartate and glutamate | asnA | asnA | |
| asnB | asnB | ||
| gltD | gltD | ||
| Arginine and proline | aspC | aspC | |
| aspD | aspD | ||
| proC | proABC | ||
| argBCDEFJ | argBCDFJ | ||
| argGH | argGH | ||
| Histidine | hisABCDFGHIZ | hisABCDFGIZ | |
| hisK | hisK | ||
| Phenylalanine, tyrosine and tryptophan | aroABCEGK | aroABCEGK | aroABCEGK |
| aroD | aroD | ||
| trpB | trpB | ||
| tyrA | tyrA | ||
| pheA | pheA | ||
| Vitamins and cofactors | |||
| Thiamin | thiCFGH | thiCFGH | thiH |
| thiD | thiD | ||
| thiI | thiI | ||
| thiN | thiN | thiN | |
| isc | isc | isc | |
| Riboflavin | ribABDH | ribABDH | |
| ribC | ribC | ribC | |
| Vitamin B6 | pdxA | ||
| pdxK | |||
| pdxS | pdxS | ||
| Nicotinate and nicotinamide | nadABC | nadABC | |
| nadD | nadD | nadD | |
| nadE | |||
| Pantothenate | panBC | panBCD | |
| panE | panE | ||
| Coenzyme A | coaX | coaX | |
| coaBC | coaBC | ||
| coaD | coaD | coaD | |
| coaE | coaE | coaE | |
| Biotin | bioA | bioAD | |
| bioB | bioB | ||
| birA | birA | birA | |
| Folate | pabABC | pabABC | pabC |
| folA | folA | ||
| folBEKP | folBEKP | ||
| folC | folC | ||
| Vitamin B12 | hemBCD | hemABCDL | |
| hemN | hemN | ||
| cbiABCDEFGHJKLPT | cbiABCDEFGHJKLPT | cbiA | |
| cobCDSTU | cobDSTU | cobC | |
| cobO | cobO | ||
| eutT | |||