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. 2011 Aug 3;31(31):11118–11125. doi: 10.1523/JNEUROSCI.1709-11.2011

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Copyright © 2011 the authors 0270-6474/11/3111118-08$15.00/0

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Figure 3. — Distinct photoreceptor outcomes in Nrl^b2/b2 and Nrl^−/− mice. A, Western blot analysis of cone opsins and rhodopsin in retina from 6-week-old mice of the indicated Nrl genotypes. Thrb2^−/− lane, Sample from TRβ2-deficient mice as a negative control for M opsin. B, Western blot analysis of cone opsins and TRβ2 in retina from P14 mice of the indicated Nrl genotypes. The initial induction of M opsin is pronounced in Nrl^b2/b2 mice at this juvenile age. C, Quantitative PCR analysis of M opsin, S opsin, and TRβ2 mRNA levels in retina of mice of the indicated Nrl genotypes at P17.