Table 2.
Preferential transmission of the Δ1b negative allele
| Mouse line 129/SvJ background | Total | +/+ (% + allele transmission) | +/− (% - allele transmission) |
| Δ1b +/− ♂ X wt +/+ ♀* |
92 | 14 (15%) |
78 (85%) |
| Δ1b +/− ♀ X wt +/+ ♂* |
78 | 30 (38.5%) |
48 (61.5%) |
| Expected % | 50 | 50 |
*
p < 0.05 by χ2 test when compared with 1:1 distribution. Male or female mice with the Δ1b +/− genotype were crossed with wild type mice and the resulting genotype of the progeny determined. The expected Mendelian ratios of 1:1 for +/+:+/− were not observed.