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. Author manuscript; available in PMC: 2012 Jun 26.
Published in final edited form as: J Nat Prod. 2011 Jun 8;74(6):1539–1555. doi: 10.1021/np200391c

Table 2.

Commercially Available Plant-Derived Intense Sweetenersa

compound name examples of countries in which approved
glycyrrhizin (1)b Japan
monoglucuronide of glycyrrhetinic acid (MGGR)c (2) Japan
stevioside (3)d Argentina, Brazil, Japan, Paraguay, People’s Republic of China, South Korea
rebaudioside A (4) France,e Japan, United Statesf
mogroside V (5)g Japan
phyllodulcin (6) Japan
neohesperidin dihydrochalcone (7)h European Union, Switzerland, Turkey
thaumatinh Australia, European Union, Japan
a

The purity levels for the compounds included in this table differ from country to country.

b

The salts, ammoniated glycyrrhizin and monoammonium glycyrrhizinate, have GRAS status as flavoring agents in the United States.

c

Semi-synthetic compound.

d

Refined Stevia rebaudiana extracts with stevioside as the major ent-kaurene glycoside component, are used as a dietary supplement in the United States.

e

Approved in September 2009 in anticipation of general EU approval (source: www.sweeteners.org).

f

Steviol glycoside mixtures with rebaudioside A as the major component received GRAS status in the United States in December 2008.

g

GRAS status accorded for a Siraitia grosvenorii extract of a standardarized mogroside V content accorded in January 2010 in the United States (source: www.biovitorria.com).

h

Has GRAS status as a flavoring agent in the United States.