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. 2011 Aug 19;6(8):e23556. doi: 10.1371/journal.pone.0023556

Figure 2. HDL increases glycogen synthesis in L6 cells and muscle tissue in vivo.

Figure 2

(A) L6 cells starved overnight were incubated with vehicle, HDL (50 µg protein/ml), insulin (100 nmol/L) or indicated combination for 2 h, n = 6. (B and C) GSK3α (B) and GSK3β (C) phosphorylation in lysates from incubated L6 cells at basal condition and after incubation with stimulators as (A), n = 3. (D) L6 cells were treated with palmitate (0.4 mmol/L) for 12 h followed by incubation with HDL of indicated concentrations for 2 h, n = 6. (E) GSK3β phosphorylation in lysates from incubated L6 cells under conditions as (D), n = 3. Data are expressed as means±SEM of three independent experiments performed in vitro. * p<0.05, ** p<0.01, vs vehicle; § p<0.05, vs palmitate.