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. Author manuscript; available in PMC: 2013 Jan 15.
Published in final edited form as: Cancer. 2011 May 16;118(2):326–332. doi: 10.1002/cncr.26144

Table 3.

5 year Relapse-Free Survival and 5 year Overall Survival among patients that received and did not receive bisphosphonates. Estimates are shown for all patients and according to tumor subtype.

N Patients Relapse-Free Survival
Overall Survival
N Events 5-Year Estimates (95% CI) Log-rank P N Events 5-Year Estimates (95% CI) Log-rank P
All patients
 No BIS 1410 405 0.71(0.68, 0.73) 352 0.77(0.74, 0.79)
 Yes BIS 39 8 0.81(0.64, 0.9) .28 7 0.83(0.65, 0.92) .42

Hormone Positive
 No BIS 767 171 0.77(0.73, 0.8) 144 0.84(0.81, 0.87)
 Yes BIS 24 6 0.77(0.54, 0.9) .72 5 0.8(0.53, 0.92) .59

HER2 Positive
 No BIS 250 91 0.65(0.59, 0.71) 69 0.78(0.72, 0.83)
 Yes BIS 8 1 0.87(0.36, 0.98) .24 1 0.88(0.39, 0.98) .43

Triple Negative
 No BIS 376 138 0.62(0.57, 0.67) 135 0.61(0.55, 0.66)
 Yes BIS 7 1 0.86(0.33, 0.98) .25 1 0.86(0.33, 0.98) .30