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. Author manuscript; available in PMC: 2012 Aug 19.
Published in final edited form as: ACS Chem Biol. 2011 May 6;6(8):781–788. doi: 10.1021/cb100408w

Figure 2. Peptide-based substrates are used to monitor activity of human Lon and human ClpXP.

Figure 2

(a) FRETN 89–98 is cleaved by both human Lon (black) and human ClpXP (dark gray) in the presence of ATP with different efficacies. The time course for hLon cleavage of FRETN 89–98 in the absence of ATP is shown in light gray. (b) FRETN 89–98Abu is a specific substrate for human Lon (black) and is not cleaved by human ClpXP (gray).