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. Author manuscript; available in PMC: 2012 Aug 19.
Published in final edited form as: ACS Chem Biol. 2011 May 6;6(8):781–788. doi: 10.1021/cb100408w

Figure 4. DBN93 inhibits degradation of proteins by human Lon, but not by ClpXP, as resolved by SDS-PAGE.

Figure 4

Reactions containing 10 µM λN (a) or StAR (b) protein, 1 µM human Lon and 5 mM ATP were analyzed by SDS-PAGE in the absence and presence of 10 µM DBN93 inhibitor. The band beneath StAR corresponds to an unidentified product. Casein (10 µM) digests with 1 µM hLon (c) or 2 µM ClpX and 2 µM ClpP (d) with 5 mM ATP in the absence and presence of 10 µM DBN93 were analyzed by SDS-PAGE.